This page provides high-level guidelines on which methods are applicable to your dataset. Note that this is intended as a quick-start.

Recommended overview and comparison papers:

  • denteuling2021clusteringlatrend: A tutorial and overview on methods for longitudinal clustering.

  • denteuling2021comparison;textuallatrend compared KmL, MixTVEM, GBTM, GMM, and GCKM.

  • twisk2012classifying;textuallatrend compared KmL, GCKM, LLCA, GBTM and GMM.

  • verboon2022clustering;textuallatrend compared the kml, traj and lcmm packages in R.

  • martin2015growth;textuallatrend compared KmL, LCA, and GMM.

Approaches

Disclaimer: The table below has been adapted from a pre-print of denteuling2021clusteringlatrend.

ApproachStrengthsLimitationsMethods
Cross-sectional clusteringSuitable for large datasets — Many available algorithms — Non-parametric cluster trajectory representationRequires time-aligned complete data — Sensitive to measurement noiselcMethodKML lcMethodMclustLLPA lcMethodMixtoolsNPRM
Distance-based clusteringSuitable for medium-sized datasets — Many distance metrics — Distance matrix only needs to be computed onceScales poorly with number of trajectories — No robust cluster trajectory representation — Some distance metrics require aligned observationslcMethodDtwclust
Feature-based clusteringSuitable for large datasets — Configurable — Features only needs to be computed once — Compact trajectory representationGenerally requires intensive longitudinal data — Sensitive to outlierslcMethodFeature lcMethodAkmedoids lcMethodLMKM lcMethodGCKM
Model-based clusteringParametric cluster trajectory — Incorporate (domain) assumptions — Low sample size requirementsComputationally intensive — Scales poorly with number of clusters — Convergence challengeslcMethodLcmmGBTM lcMethodLcmmGMM lcMethodCrimCV lcMethodFlexmix lcMethodFlexmixGBTM lcMethodFunFEM lcMethodMixAK_GLMM lcMethodMixtoolsGMM lcMethodMixTVEM

It is strongly encouraged to evaluate and compare several candidate methods in order to identify the most suitable method.

References